Support to the XVI SECAL Congress, by: a. Funding of a workshop on classification and notification of severity under Directive 2010/63/EU. b. Funding of a session on actions for transparency. c. Funding of abstract book.
In the Master of Laboratory Animal Science program, the knowledge acquired in Bachelor's program is specialised and deepened in scientific, laboratory animal science aspects. The graduates have a detailed knowledge of animal experiments based on the latest scientific findings in laboratory animal science. This includes all areas of planning, carrying out, evaluating and improving animal experiments in compliance with the latest legal regulations and ethical criteria as well as animal-friendly husbandry, care and care of the animals.
Laboratory Animal Science is a highly specialized and rapidly evolving field in biomedical science. Since Laboratory Animal Science has an enormously broad scope and a high impact on research with animals, competence in this field should urgently be promoted and provided in India. It is our effort to train the future scientists in the field of Laboratory Animal Science to improve their understanding and practice of scientific methods as well as implementation of animal welfare prior to their actual work with live animals. Keeping in the view of the target groups we have designed this course based on FELASA (Federation of European Laboratory Animal Science Associations) category C recommendations suited to our Indian conditions for veterinarians, Medicos, biologists, biochemists, physicians and other researchers initiating (directing or carrying out) projects based on laboratory animal experimentation.
"Too many pre-clinical experiments are giving results which cannot be reproduced. This may be because the experiments are incorrectly designed. In “Completely randomized” (CR) and “Randomised block” (RB) experimental designs, both the assignment of treatments to experimental subjects and the order in which the experiment is done, are randomly determined. These designs have been used successfully in agricultural and industrial research and in clinical trials for nearly a century without excessive levels of irreproducibility. They must also be used in pre-clinical research if the excessive level of irreproducibility is to be eliminated.A survey of 100 papers involving mice and rats was used to determine whether scientists had used the CR or RB designs. The papers were assigned to three categories “Design acceptable”, “Randomised to treatment groups”, so of doubtful validity, or “Room for improvement”. Only 32±4.7% of the papers fell into the first group, although none of them actually named either the CR or RB design.If the current high level of irreproducibility is to be eliminated, it is essential that scientists engaged in pre-clinical research use “Completely randomised” (CR), “Randomised block” (RB), or one of the more specialised named experimental designs described in textbooks on the subject."
The purpose of my Ph.D.-project is to investigate mechanisms involved in chronic pain. I focus on a cell type that under normal conditions support our pain-sensing nerve cells but are proposed to contribute to the painful sensation that follows physical injury or chemotherapy treatment. By investigating the response in this cell type following physical injury or chemotherapy, we will come one step closer to understanding how nerve cells in some cases are affected to signal more intense or chronic pain. Animal Experiments are essential for investigating my questions at hand, and often require a surgical procedure on the sciatic nerve to evoke neuropathic pain in the laboratory animal. When I perform this procedure, it is crucial that I excel, to minimize suffering in the experimental animal. Therefore, I apply for funding to participate in Ph.D. courses to develop my skills in experimental surgery.
This project consists of shooting a science divulgation video titled “En ciencia todo suma” (“In Science Everything Counts”) which will be distributed among all our association members by all channels available: SECAL’s web site, email distribution list, YouTube, Twitter, etc. This video will show the human side of our career together with a scientific message to society aiming to provide why is animal experimentation needed. It will be realistic, hilarious, interactive and committed to Animal Welfare and Science. This video will show caretakers, technicians and investigators together with written material that reveal in an entertaining way our human side.